https://ymaho.com/mesenchymal-drift-a-new-mechanism-of-aging-and-alzheimer-s-treatment
Discovery of mesenchymal drift — key to cell rejuvenation. A clinical trial for Alzheimer's disease treatment starts with 240 patients. Learn more.
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https://ymaho.com/harvard-scientists-the-role-of-peroxisomes-in-extending-life-during-fasting
Nature Aging: Harvard revealed how fasting extends life through peroxisomes and the PRX-5 protein. A new target for rejuvenating interventions. Read the details.
https://ymaho.com/antidepressant-mianserin-extends-life-nature-communications-study
Nature Communications study: old antidepressant mianserin restores calcium homeostasis, extends mouse lifespan by 30%, and fights aging. Learn the mechanism and repositioning prospects.
https://ymaho.com/calcium-signaling-the-key-to-slowing-aging
Scientists have linked calcium homeostasis to slowing aging through S100A6 and PARP1. Mianserin reverses the process. Read the analytical review in Nature Communications.
https://ymaho.com/mianserin-treatment-of-progeria-increased-lifespan
Nature Communications study: antidepressant mianserin restores calcium homeostasis and prolongs life in mice with progeria and aging mice. Learn about the S100A6 and cGAS-STING mechanism.
https://ymaho.com/gene-therapy-of-aging-in-the-russian-federation-rage-blockade-and-sarcopenia-exosomes
Russian scientists are creating the world's first anti-aging drugs: RAGE gene blocker and exosome rejuvenation. The Ministry of Education and Science promises clinical use by 2030. Learn how transplantation of 'young' vesicles restores muscles and why the budget exceeds 2 trillion rubles.
https://ymaho.com/gene-vgll3-mechanism-of-aging-and-cancer-nature-communications
Discovery of the vgll3 gene confirms the theory of antagonistic pleiotropy: accelerated growth leads to aging and cancer. Learn about the implications for longevity research.
https://ymaho.com/dream-protein-key-regulator-of-aging-and-mutations-nature-aging
Nature Aging study: the DREAM complex controls aging and mutational burden. How reducing its activity extends lifespan and protects against Alzheimer's disease. Read.
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