Search Articles — Sudonull

https://sudonull.com/merkle-tree-on-go-generics-and-proof

Implementation of Merkle Tree on Golang with generics. Proof of inclusion in O(log N), CBOR hashing, code examples. For middle/senior dev — study and apply in blockchains.

https://sudonull.com/compiler-from-scratch-lexer-parser-type-inference

Experience creating a compiler for my own language: from lexer to LLVM IR. Handling generics, lambdas, linking. For middle/senior developers. Learn approaches without deep knowledge.

https://sudonull.com/zero-allocation-io-for-go-contests

Six solutions for fast input-output in Go without allocations: bufio.Reader, generics, scratch-buffers. Benchmarks, code, inline-utility. For middle/senior developers.

https://sudonull.com/hkt-in-typescript-emulation-and-practice

Learn how to emulate Higher-Kinded Types in TypeScript without code duplication. Kind-mappings, hkt-toolbelt libraries, implementation challenges. For middle/senior dev.

https://sudonull.com/genetic-adaptation-after-the-neolithic-paleodna-data

Analysis of 15 thousand ancient genomes proved acceleration of evolution after agriculture. How the GLMM method revealed 479 adaptive mutations. Learn the details of the study.

https://ymaho.com/fda-to-review-generic-dexmethylphenidate-ctx-1301

FDA to Rule on CTx-1301 May 31 — New ADHD Drug with Up to 12 Hours of Action Without Booster Doses. Learn How This Will Change Therapy for Children and Adults.

https://ymaho.com/genetically-modified-virus-stopped-pancreatic-cancer-breakthrough

Oncolytic adenovirus from the University of Minnesota halted tumor growth in three patients with pancreatic cancer. Learn about the mechanism, risks, and prognosis.

https://ymaho.com/dream-genetic-switch-link-between-lifespan-and-diseases

Low DREAM activity increases lifespan in 92 species and protects against Alzheimer's disease. Learn about the genetic switch of aging and its impact on the risk of age-related diseases. Read details.

https://ymaho.com/ai-predicts-meningioma-recurrence-without-genetics-2026-analysis

Mayo Clinic created AI analyzing tumor slides to predict meningioma recurrence without DNA methylation. Accuracy comparable to genetics. Learn how this changes neuro-oncology.

https://ymaho.com/smart-drugs-for-cancer-and-hiv-development-by-siberian-scientists

Institute of the Siberian Branch of the Russian Academy of Sciences creates therapeutic oligonucleotides — molecules that switch off cancer and HIV genes. The development of phosphorylguanidines promises treatment without side effects. Learn how Russian genetic engineering bypasses Western patents.

https://ymaho.com/personalized-crispr-therapy-saved-an-infant-in-vivo-breakthrough

A child with the ultra-rare CPS1 mutation survived thanks to personalized CRISPR therapy in 6 months. Learn about the breakthrough in genetic engineering and N-of-1 platforms.

https://ymaho.com/crispr-cas3-treatment-of-duchenne-muscular-dystrophy-deletion-of-exons-45-55

Japanese geneticists used CRISPR-Cas3 to delete long DNA segments in Duchenne muscular dystrophy. The method is suitable for 60% of patients. Details in the article.

https://ymaho.com/pig-kidney-transplant-to-human-69-genome-edits

Surgeons transplanted a genetically modified pig kidney with 69 edits into a patient. The organ worked for 271 days — learn how this addresses the donor crisis.

https://ymaho.com/stimage-ai-tool-for-detecting-hidden-cancer

STimage AI predicts cancer genetics from standard histology, making spatial biology nearly free. Learn how it will change diagnostics and the market.

https://ymaho.com/gene-therapy-opgx-lca5-accepted-into-fda-rdep-program

Learn how Opus Genetics' gene therapy OPGx-LCA5 received RDEP status from the FDA, accelerating the development of treatment for ultra-rare LCA5 blindness in children. Detailed analysis and prospects.