MIT nanoparticles for immunotherapy of pancreatic cancer metastases https://ymaho.com/mit-nanoparticles-for-immunotherapy-of-pancreatic-cancer-metastases
MIT scientists have created nanoparticles with AND logic for targeted activation of the STING pathway in metastases. Preclinical data: 70% reduction in metastases. Learn about the breakthrough in nanomedicine.
CD4+ T cells kill cancer through ferroptosis: a breakthrough in immunology https://ymaho.com/cd4-t-cells-kill-cancer-through-ferroptosis-a-breakthrough-in-immunology
Scientists have proven: CD4+ T lymphocytes destroy MHC I-negative tumors through ferroptosis. The discovery changes the approach to cancer immunotherapy and treatment of GVHD. Read the details.
New microproteins in junk DNA: 1700+ peptideins reveal targets for immunotherapy https://ymaho.com/new-microproteins-in-junk-dna-1700-peptideins-reveal-targets-for-immunotherapy
TransCODE scientists discovered over 1700 microproteins in non-coding DNA. Silencing the OLMALINC gene reduces cancer cell survival by 85%. Learn how peptideins are changing oncology and immunotherapy.
Peptideins from 'junk' DNA: 1700 new microproteins kill cancer https://ymaho.com/peptideins-from-junk-dna-1700-new-microproteins-kill-cancer
Scientists have discovered over 1700 microproteins in non-coding DNA, becoming new targets for cancer. Learn how peptideins change immunotherapy and oncovaccines. Read breakthrough details!
New type of cellular 'immune bomb': ruptosis against cancer https://ymaho.com/new-type-of-cellular-immune-bomb-ruptosis-against-cancer
Mechanism of ruptosis discovered: kamikaze cells explode, destroying tumors locally. Learn how this will change cancer immunotherapy and infection control.
Moderna vaccine shrank tumors in 83% of melanoma patients https://ymaho.com/moderna-vaccine-shrank-tumors-in-83-of-melanoma-patients
mRNA drug mRNA-4359 with Keytruda showed 83% response and 17% complete remissions. Even PD-L1-negative tumors shrank. Learn how a ready-made vaccine teaches the immune system to attack cancer without personalization.
FDA approval of combination immunotherapy for bladder cancer: durvalumab + BCG https://ymaho.com/fda-approval-of-combination-immunotherapy-for-bladder-cancer-durvalumab-bcg
FDA approved durvalumab with BCG for high-risk NMIBC. POTOMAC data: 32% risk reduction. Analysis of efficacy, toxicity, and consequences of BCG shortage. Learn more.
Immunotherapy for BRAF Colorectal Cancer: New Data from Nature Medicine https://ymaho.com/immunotherapy-for-braf-colorectal-cancer-new-data-from-nature-medicine
Analysis of the efficacy of encorafenib and binimetinib combination in BRAF-mutant colorectal cancer. Results, limitations, prognosis, and side effects. Read more.
Immunotherapy for endometrial cancer: ASCO 2026 data https://ymaho.com/immunotherapy-for-endometrial-cancer-asco-2026-data
Analysis of the NRG-GY018 study: pembrolizumab + chemotherapy improved survival in endometrial cancer. Risk of death reduced by 44% in dMMR. Details at ASCO 2026.
Lung cancer drug Lurbinectedin approved in Europe https://ymaho.com/lung-cancer-drug-lurbinectedin-approved-in-europe
Europe approved the world's first Lurbinectedin drug with immunotherapy for aggressive lung cancer. 46% reduction in risk of death. Learn about the breakthrough and forecasts.