Life extension, part 0.1 - Long-term brain and body health

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If I live to 90+ years, how can I stay active, intelligent and beneficial and enjoy the people around me from 70 to 90+ years?


How not to become lethargic and demanding care individual who can only consume the series, drink and talk about the past?


How can you create, change the world, explore space and time and your mind until death?


This article is the second and is written based on the results of interest and comments on the first article on the selection of supplements for brain health.


In fact, this is a prequel and the article should be the first. In it, I summarize the experience of several books and studies on how:


  • Extend life.
  • Until the end of life remain vigorous and intelligent.

So, let's go to understand.


Imagine, when we, for example, are 70 years old or more, the sum of our experience becomes very large. Our brain accumulates a huge amount of information, life experience and, perhaps, at this moment we can create something great. Or just to live is very interesting and bright and to learn new things, because it’s already likely that domestic and other problems have been settled.


But, unfortunately, the statistics are against us. From the age of 65, cognitive functions are inhibited, the amount of energy in the body decreases and we begin to shrink, diminish, disappear from space, including the space of our mind - the mind becomes sluggish, thinks slowly, loses vitality, forgets everything.


For example, the percentage of Alzheimer's in the United States (and there are still many different diseases and not just the brain):
65 years old - 10%;
85 years old - 50%.


A lot of research efforts are directed at this disease, as its development affects not only the patient, but also the people around him and relatives (link wikipedia https://goo.gl/aZah1W )


Let's analyze the ways of how to increase the likelihood that we will live a long time and until we die, be active, active and benefit the people around us without fanaticism.


So the goal is body health + an active thinking brain to death at about 90+ years old. Full independence, the ability to travel, work, have fun, live a full life, etc.


An important condition for achieving the goal is without fanaticism and excesses, for example, without spending a lot of time on food and obsessively thinking only about calories or settling in the mountains and living alone avoiding stress. That is, the task is to remain socially active, live in an environment that you like, communicate, make friends, benefit people.


Plus a reservation - when the goal is not fixed for a period of 90+ years. You can die at any time and it should not cause fear, depression, etc.


Based on the analysis of books, articles, applicability in a socially full life and personal experience, I arranged in order of importance actions that will help to live a long and healthy life.


Disclaimer - I am not a doctor and the main goal of the article is to classify my experience and read books and, perhaps, give an initial impetus to those who are interested in themselves starting to read and think about this topic. I do not pretend that this is true, I will be grateful for constructive criticism and corrosive questions.


In order of importance, a full analysis of each item below:


  1. Regular checks at the doctor - blood test, condition analysis, etc. (Below is a real example of verification with analyzes).
  2. Walking down the street, from 4 to X km per day.
  3. Nutrition.
  4. Sport - flexibility, elasticity, energy.
  5. Life style.
    1. Self education about the brain.
    2. Meditation - (mark for the future - neural
      connections, translation of 2 large studies)
    3. Exercises for the brain - hobbies.
  6. Technological Life Extension
    1. Supplements for the brain. ( first article )

(For those who read the first article, the supplement is, I think, the last important point from which the methodology of modern life extension and brain activity increase begins. But without the first six points, this is unlikely to help us much.)


1. Regular check-ups with a doctor (super important)


Imagine how offensive it is to go in for sports, eat right, buy super ecological food, bathe in sleep, etc. and to die is painful and difficult at 60. Or start to blunt at 65. Why can this be?


We are lamers in medicine. A huge number of diseases. Their manifestations are very different, complex, interdependent. A good doctor studies for 6 years, then he gains experience for a long time, he improves his level, he constantly treats people.


When the doctor examines us and observes, he can pay attention to such bugs of our body, about which we will never think. And these bugs can lead to premature death or to the fact that in our body there will be a constant inflammation or increased production of harmful substances and as a result in 70-80 years we will grow vegetables and stupid, since the brain has developed and became sick.


They write about it in books, it is confirmed by statistics, it is confirmed by elementary logic - all the bugs are better to catch the diseases of the body in the early stages and to properly heal.


And you don’t have to do it yourself, it’s harmful, there are professionals for it.


Anything can happen here - cancer, gastritis, liver diseases, various parasites, various disorders of the immune system, lack of elements, etc.


What is checked? It is to come to a good therapist, it is advisable to go to the same thing, he looks at you, polls you, you answer him honestly.


Then he thinks, analyzes and gives you directions for tests and examinations. The point is that he does not direct you to 1000 tests, but asks you to do exactly what you need and relies on your education, your examination and palpation, your survey and your experience.


Then you do everything the doctor said, he analyzes the results and, if necessary, prescribes additional tests.


Then he says that everything is ok (rarely) or what needs to be done to maintain health, fix those bugs that were found this time.


Personally for myself, I decided that it was stupid to save money on this and I went to an expensive clinic for a good doctor. But it is necessary to choose not at the price and payment, but according to reviews and how the doctor is immersed in your case. I am not at all a fan of paid medicine and, with a limited budget, it is quite possible to do everything the same thing for free, we just spend energy not on making money, but on organizing this free process.


The promised example is in mice itself.


I go to the therapist every 2 years. Last time was this year in August, I will give for example from the photo how it all happened. The purpose of the example is to show that this is necessary and important.


My analyzes and doctor's recommendations (neatly - many photos)

Так как врач меня знает, то она расспросила как я жил эти два года, где побывал, как себя чувствую. Также подробно про питание, спорт, работу, другую активность.


Замерила, взвесила, послушала.


Потом выслушала жалобы. Была одна — уплотнение на руке.


Осмотрев его сказала, что это нейрофиброматоз, есть почти у всех, можно не париться, будет появляться по мере увеличения прожитых лет еще. Желательно поменьше загорать.


По результату назначила анализы крови в минимальном наборе + мочи + УЗИ.








Посмотрев их заранее и проанализировав на приеме рассказала, что все супер, жить буду, но:


  1. запасы железа приближаются к нижней границе (я не ем мяса и поэтому она назначила этот анализ) и хорошо бы попить железа
  2. кой чего (на картинке ниже) желательно попить для поддержки моего ливера (рассказывала точно, но так как я ей доверяю, то не запоминал)
  3. один параметр Эозинофилы выше нормы и значит у меня или аллергия на что-то, или, так как я по полгода живу в Азии и Индии, паразиты.

Поэтому назначила дополнительные анализы.





По результату обнаружен Бластоцитоз. Опять таки врач сказала, что вообще ничего страшного и он есть у очень многих, но, так как у меня они начали развиваться и привели к повышению этого параметра, то желательно от них избавиться.


В результате назначила дополнительно попить таблетки максимально мягкие и безвредные, чтобы от них избавиться + через 3 дня после приема курса этих таблеток дополнительный анализ на этих паразитов. Если все ок, то можно к ней идти через следующие два года. Если останутся, то будем дальше разбираться.


Итоговый результат ниже.




So, if I hadn’t done this routine inspection, despite my healthy diet and sports, I would still live with constant inflammation, which would cause many toxins in my body, which in the long term would lead to a decrease in the efficiency of the brain and decrease duration and quality of life.


Once again, there are a lot of variants of our body’s bugs. Professionals must work with this. It is not necessary to climb into this lamers without education, work experience and regular work in this area.


In the end, I hope everything is clear here and I convinced you that this is the most important point that is directly related to the fact that we can live for a long time and in our old age we did not have strong illnesses and a sluggish brain.


2. Walking down the street, from 4 to X km per day.


I have been walking every day for 4 and more kilometers for 10 years already and for me the use of walking is obvious from personal experience. I put walking on the second place in importance, as this is the most accessible type of physical activity for all of us, easily incorporated into daily life and which has the following proven advantages:


  1. General improvement in health, longer life
  2. Improving the performance of the heart, preventing death from heart attacks
  3. Regulation of digestion and weight: one and two
  4. Improve mental and cognitive abilities
  5. Sleep improvement
  6. many more other advantages.

Also for me a big plus is that you can walk with friends or children and this time becomes a time of communication and communication. At home, everyone is always busy, computers, games, TV, work, etc. And so it turns out that an hour a day, or more, I communicate with people interesting to me.


In addition to the above advantages, many others can be found, but they are often written in such a manner that they are more likely to scare away than to motivate you for daily walks. For example, an article with strong statements such as “Regular daily walking has been found to be able to repair old DNA” which does not have a single source. And therefore there is no trust right away. (I do not know whether this is so or not)


How to walk?


Not by the sun and not along the roads. In Asia, perfect at sunset, in St. Petersburg at any time.


For example, in St. Petersburg, in the area of ​​Komendantsky Avenue, we are walking with our son. This is a sleeping area with large roads and buildings. Therefore, we have laid a route across yards and along green areas. It is better not to walk along the roads in Russia or Asia, as the exhaust from the cars is not useful.


Also for walking it is good to buy special shoes for winter - in St. Petersburg it is slush and dirt + a sports jacket, which is not blown and with a good drawling hood. If you dress properly, then even in the winter in the wind, a little rain and slush is pleasant to walk.


During the walks (or immediately after them), various problems and interesting ideas come to mind. The brain really relaxes and then comes a surge of strength to work or work or a good rest.


It is interesting for one of them to walk to vigorous music, for example, I already had my own soundtracks, under which I can walk endlessly.


3. Power


Everything is simple - our body is a complex unique thing (I do not know what to call it),
which processes food for energy, regeneration, maintenance and renewal of the structures of our body. All the elements for this we take from food. For example, there is always in McDonalds and taking supplements for the brain is stupid.

It is better to spend money and moral strength to change the pattern of power.


There are many many books on this subject, a huge amount of money is spinning around in the industry, so it's not easy to figure it out, but you need to try. I would recommend to read the " Chinese study. The results of the most extensive study of the
relationship of nutrition and health
."


It seemed interesting to me and I was the only one in whom I met a description of how medical research is conducted, how the probability of the influence of any factors on the occurrence and development of a disease is calculated.


Excerpt for example (many bukoff)

Корреляция и причинно следственная связь


Во многих исследованиях вы обнаружите, что слова «корреляция» и «ассоциация»
используются для описания взаимосвязи между двумя факторами, возможно даже
представляющими собой причинно следственную зависимость. Эта идея в значительной
степени используется в «Китайском исследовании». Анализируя ситуацию в 65
округах, 130 деревнях, среди 6500 взрослых и их семей, мы выясняли, существует
ли взаимосвязь между разными особенностями питания и образа жизни и
возникновением болезней. Если, к примеру, потребление белка больше среди
населения, у представителей которого наблюдается высокая частота рака печени, мы
можем сказать, что существует положительная корреляция, или взаимосвязь, между
потреблением белка и этим заболеванием: при увеличении одного показателя
наблюдается рост другого. Если прием в пищу белка выше среди населения,
представители которого редко страдают раком печени, мы можем сказать, что между
употреблением белка и раком печени существует обратная взаимосвязь. Иными
словами, изменение этих двух показателей происходит в противоположном
направлении: когда один растет, другой снижается.


В нашем гипотетическом примере, если существует корреляция между употреблением в
пищу белка и возникновением рака печени, это не доказывает, что белок вызывает
или предотвращает данную болезнь. Классической иллюстрацией этой сложности
служит тот факт, что в странах с большим количеством телефонных столбов чаще
наблюдаются сердечно сосудистые и многие другие заболевания. Таким образом,
существует положительная корреляция между телефонными столбами и сердечно
сосудистыми заболеваниями. Однако это не доказывает, что телефонные столбы
вызывают такие заболевания. На самом деле корреляция не означает причинно
следственную связь.


Из этого не следует, что корреляция бесполезна. Когда она правильно
интерпретируется, то может быть эффективно использована для изучения взаимосвязи
питания и здоровья. Например, в «Китайском исследовании» содержится более 8000
случаев статистически значимой корреляции, и это имеет огромное значение. Когда
наблюдается так много подобных случаев корреляции, ученые начинают выявлять
взаимосвязь между образом жизни, питанием и болезнью. Это, в свою очередь,
помогает понять, как процессы питания и здоровья, которые обычно невероятно
сложны, происходят на самом деле. Однако в случае, если кто то хочет получить
доказательства того, что единственный фактор может привести к единственному
результату, корреляция – не очень хороший инструмент.


Статистическая значимость


Вам может показаться, что определить наличие корреляции между двумя факторами
очень просто: либо они коррелируют между собой, либо нет. Но это не так. Когда
вы рассматриваете большое количество данных, вам нужно провести статистический
анализ, чтобы определить, имеется ли корреляция между двумя факторами. Ответом
не будет однозначное «да» или «нет». Это вероятность, которую мы называем
статистической значимостью. Статистическая значимость – это мера измерения
того, можно ли считать полученный результат эксперимента надежным или он всего
лишь обусловлен случайными факторами. Если вы трижды подбросите монету и трижды
выпадет орел, то, скорее всего, это случайность. Если же вы подбросите монету
сто раз и каждый раз будет выпадать орел, вы можете быть полностью уверены, что
у этой монеты орел с обеих сторон. В этом и заключается идея, лежащая в основе
понятия статистической значимости: это вероятность, что корреляция (или другие
результаты) действительно существует, что это не игра случая.


Считается, что результат исследования статистически значим, если вероятность
того, что он обусловлен случайными факторами, менее 5 %. Это означает, например,
что существует 95 процентная вероятность того, что при повторном исследовании мы
получим тот же результат. Точка отсечения на уровне 95 % произвольна, тем не
менее это стандартный показатель. Другая произвольная точка отсечения – 99 %.
Если результат соответствует этому показателю, говорят, что он имеет высокую
статистическую значимость. В приведенном в этой книге анализе питания и
болезней время от времени используется понятие статистической значимости, и оно
может применяться для оценки надежности, или весомости, доказательства.


Механизм действия


…...


А знание механизма действия подкрепляет доказательство. Иными словами, это
означает, что два коррелирующих фактора взаимосвязаны биологически
правдоподобным способом. Если взаимосвязь правдоподобна с биологической точки
зрения, она считается гораздо более убедительной.


Метаанализ


Наконец, мы должны понимать идею метаанализа. Метаанализ заключается в
объединении данных из различных исследований и их анализе как единого набора
данных. Результат может стать гораздо более убедительным после аккумулирования и
анализа большого массива информации.



My personal opinion about nutrition is that it should gradually and reasonably improve and become more and more healthy as we get older - aging.


If we take a certain conditional scale starting from the most harmful to the most useful, then I would make it like this:


  1. (the most harmful)
    soda
  2. fast food
  3. all sorts of quick sweets - chocolate bars, sweets, etc.
  4. fast food - muesli, pizza, dumplings, etc., etc.
  5. fatty fried meat
  6. meat
  7. milk and dairy products
  8. a fish
  9. (the most useful)
    food from whole grains, vegetables, nuts, vegetable oils

It's just some kind of conditional scale for yourself. For example, I am with friends in a
restaurant. I would love to eat seafood pizza or falafel. At the same time,
one at home will better cook buckwheat with sauces and salad.


If you don’t fanatically, then a certain optimal and non-stressful
mechanism of providing yourself with tasty food is gradually produced .


4. Flexibility, muscle elasticity, energy.


The man at his birth is tender and weak,
and at the onset of death is firm and strong.
All creatures and plants at their birth are tender and weak,
and when they die, they are dry and rotten.
Firm and strong is that which perishes,
and gentle and weak is that which begins to live.
Lao Tzu “Tao Te Ching”


Old age is often visually associated with hunchedness and rigidity — a person cannot normally stretch, bend, move vigorously, etc. This happens for two reasons:


  1. due to the fact that our hip joints + everyone else loses mobility
  2. back muscles stop holding the spine

IMPORTANT. Internal (not external beautiful bitsuha) muscles lose tone and therefore we begin to sink and our entire body works worse.


Many and often write about what kind of sport is useful when considering it over a long period of time with an integrated approach to the state of health. Someone writes a good swim, someone to go to strength training (swing or fitness), someone running or cycling, someone play sports. Contribute to this variety.


First I want to define the parameters of the task - up to 90+ years we must:


  1. remain mobile, do not skukozhitsya, the joints are not sick, walk, wear things, etc.
  2. be able to travel independently
  3. our brain should work well

For this task, you can already highlight the requirements for the sport:


  1. the elasticity of the inner muscles, the mobility of the joints must be maintained (a beautiful outer one, starting from a certain age, is no longer so important)
  2. back, knees, elbows, etc. - must be alive, vigorous, able to walk, take light load
  3. we must be able to maintain balance and orientation in space (stand on one leg, for example, tie shoelaces, reach somewhere)
  4. the lungs must be developed very well to give a lot of oxygen to the body and brain

An additional requirement is that I travel and want to be able to play sports anywhere in the world. I can be in Hong Kong, in a country house near St. Petersburg, in the south of the sea, in Berlin in a hotel, etc.


Options:


  1. Fitness, rocking - is harmful for the joints, work with the superficial layers of muscles, work with certain areas that is harmful. Harmful to vessels - large weights and inadequate load on the legs (varicose and tp)
  2. Bicycle is stressful with you, it is not always possible to ride, in Russia or Asia, in general, everything is not very suitable for this.
  3. Running - almost everything is super, but knees, joints.
  4. Swimming is great, but there’s not always where to swim + lots of bleach pools.
  5. Game sports - traumatic, must be studied separately.
  6. Yoga is super.

The result of my personal selection is yoga. All the rest did not suit me in any of the above parameters.


In yoga, everything is so balanced that for me it looks like a gift. When you start to make a list of what yoga allows you to maintain normal, it looks like an advertisement, so I reduced it to the main one.


For me, almost the most important thing is, after some period of study in the studio, it is quite possible to study independently in any part of the world, including a small hotel room.


Normal yoga class balanced supports, improves and works with:
(proof on the links below)


  1. joint mobility
  2. deep back muscles
  3. lungs and breathing
  4. balances
  5. strength and endurance
  6. internal organs of the digestive system
  7. with concentration of mind

Since I have been studying these issues for a long time and have been practicing yoga for about 8 years (in 2009, at once to find out which yoga suits us, we organized a yoga festival, where communicating with teachers from the inside, as the organizers, learned many nuances), I wanted to tell a couple of things:


  1. There are different types of yoga, from my point of view, geeks and sensible people are suitable or Ashtanga yoga or Iyengar yoga. Personally, I come up ashtanga yoga - this is a very intense type of yoga, and even for athletes there is where to have fun. Also for me, plus the fact that they immediately give a sequence that you can do yourself - at home or anywhere (indoors).
  2. There are different clubs and instructors - there are bad, there are good ones. All the same as everywhere else. Just like a doctor, it can be good, it can be bad. If you choose, use your geek brain. In St. Petersburg or Moscow, I can advise you to study yoga places and instructors in PM, since I have studied the topic for a long time and carefully. In Ashtanga Yoga, plus that in order to become a teacher, a person must invest a lot of time and effort in this. You cannot complete the course for 200 hours and start teaching there. This gives some additional feeling of confidence that the teacher will not advise something wrong.

By the way, in Germany, my Mum pays yoga for health insurance, as there it is considered a proven procedure for recovery after certain diseases. Here is a meta-analysis with recommendations to use yoga for the treatment of chronic back pain www.ncbi.nlm.nih.gov/pmc/articles/PMC3805350 (it emphasizes that there should be an experienced teacher)


There are quite a few modern studies on this topic:


  1. Useful to cores
  2. Benefits of Depression
  3. Back
  4. Oxygen, hypoxia

Here there are good personal reviews of geeks about yoga - what does it give them http://yoga-shala.ru/blog/ashtanga-faces/


Conclusion: yoga can be a sport that is always with us and allows us to comprehensively support our body in the norm - muscles, flexibility, lungs, oxygen saturation.


Yes, and mega bonus for male geeks - yoga has a very large% of girls — beautiful, well-nourished, and without terrible fitness glamor.


That's all for now, the resulting sheet of text scares me a little. If you are
interested in the continuation, write pliz in the comments or in a personal.



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Our other research articles





Recommended complex for daily intake:

Omega-3
Vitamin D
Set of minerals
Daily 1 serving of protein, better in the morning

Fish oil and vitamin D are very important for the brain and for the body, minerals and protein are important for the long-term health of the body. It is advisable to take those who are over 30 years old.

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